Brief Information of the Compound and Protein
Compound Name
1-[[4-(hydroxycarbamoyl)phenyl]methyl]-3,4-dihydro-2H-quinoline-6-carboxamide
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PubChem ID
CID: 156024937
Canonical SMILES
NC(=O)c1ccc2N(Cc3ccc(cc3)C(=O)NO)CCCc2c1
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Compound Formula C18H19N3O3
Compound Structure
Protein Name
Histone deacetylase 6
Protein Classification
Epigenetic regulator
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Eraser
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Histone deacetylase
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HDAC class IIb
Uniprot ID
Q9UBN7
Gene Name
HDAC6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1370 nM
   TI
   LI
   LO
   TS
CL000186 RPMI-8226 Homo sapiens (Human)  1
1
EC50 = 140 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.7 nM