Brief Information of the Compound and Protein
Compound Name
2-((1R,2S,5S)-2-Benzyl-3-azabicyclo[3.1.0]hexan-3-yl)-6-morpholinopyrimidin-4(3H)-one
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PubChem ID
CID: 156458276
Canonical SMILES
O=c1cc(N2CCOCC2)nc(N2C[C@H]3C[C@H]3[C@@H]2Cc2ccccc2)[nH]1
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Compound Formula C20H24N4O2
Compound Structure
Protein Name
Serine-protein kinase ATM
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
Q13315
Gene Name
ATM
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.2 nM