Brief Information of the Compound and Protein
Compound Name
4-(7-methoxy-9H-thioxanthen-4-yl)-2-morpholin-4-yl-1H-pyrimidin-6-one
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Canonical SMILES
COc1ccc2Sc3c(Cc2c1)cccc3-c1cc(O)nc(n1)N1CCOCC1
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Compound Formula C22H21N3O3S
Compound Structure
Protein Name
Serine-protein kinase ATM
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
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Atypical protein kinase PIKK family
Uniprot ID
Q13315
Gene Name
ATM
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 6700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 25 nM