Brief Information of the Compound and Protein
Compound Name
[(3R)-3-aminopiperidin-1-yl]-[4-(3-isoquinolin-6-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]methanone
    Show/Hide
Canonical SMILES
N[C@@H]1CCCN(C1)C(=O)c1ccc(cc1)-c1ccc2ncc(-c3ccc4cnccc4c3)n2n1
    Show/Hide
Compound Formula C27H24N6O
Compound Structure
Protein Name
MAP kinase-interacting serine/threonine-protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MNK subfamily
Uniprot ID
Q9BUB5
Gene Name
MKNK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 9.4 nM
   TI
   LI
   LO
   TS