Brief Information of the Compound and Protein
Compound Name
4-[(4-ethylpiperazin-1-yl)methyl]-N-[3-[(6-methoxyimidazo[1,2-b]pyridazin-3-yl)methylamino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
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Canonical SMILES
CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(NCc3cnc4ccc(OC)nn34)c2)CC1
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Compound Formula C30H34F3N7O2
Compound Structure
Protein Name
Macrophage colony-stimulating factor 1 receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase PDGFR family
Uniprot ID
P09581
Gene Name
CSF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000124 NFS-60 Mus musculus (Mouse)  1
1
IC50 = 406 nM
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