Brief Information of the Compound and Protein
Compound Name
6-(2-chlorophenyl)-8-methyl-2-(3-methylsulfonylanilino)pyrido[2,3-d]pyrimidin-7-one
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PubChem ID
CID: 135382283
Canonical SMILES
Cn1c2nc(Nc3cccc(c3)S(C)(=O)=O)ncc2cc(-c2ccccc2Cl)c1=O
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Compound Formula C21H17ClN4O3S
Compound Structure
Protein Name
Receptor-interacting serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RIPK family
Uniprot ID
O43353
Gene Name
RIPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 > 4000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM