Brief Information of the Compound and Protein
Compound Name
6-methoxy-N,N-dimethyl-2-(4-methylpiperazin-1-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
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Canonical SMILES
COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N1CCN(C)CC1)N(C)C
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Compound Formula C23H36N6O2
Compound Structure
Protein Name
Toll-like receptor 7
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NYK1
Gene Name
TLR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000686 HEK-Blue hTLR7 Homo sapiens (Human)  1
1
IC50 = 2160 nM
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