Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,35S,38S,41S,44S,47S)-47-((2S,5S,8S,11S,14S,17S,20S,23S,24R)-11-((1H-indol-3-yl)methyl)-20-(2-amino-2-oxoethyl)-8-(3-amino-3-oxopropyl)-23-carbamoyl-24-hydroxy-14-isobutyl-5-isopropyl-17-(2-(methylthio)ethyl)-3,6,9,12,15,18,21-heptaoxo-1-phenyl-4,7,10,13,16,19,22-heptaazapentacosan-2-ylcarbamoyl)-44-(3-amino-3-oxopropyl)-20-(4-aminobutyl)-2-benzyl-11-(2-carboxyethyl)-29-(carboxymethyl)-35,38-bis(3-guanidinopropyl)-14,23-bis(4-hydroxybenzyl)-5-((R)-1-hydroxyethyl)-8,17,32-tris(hydroxymethyl)-26-isobutyl-41-methyl-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxo-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46-pentadecaazanonatetracontane-1,49-dioic acid
    Show/Hide
Canonical SMILES
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)C(Cc1ccccc1)C(=O)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(N)=O)[C@@H](C)O
    Show/Hide
Compound Formula C135H197N35O42S
Compound Structure
Protein Name
 Protein Info 
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
>
Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 267.4 nM
   TI
   LI
   LO
   TS