Brief Information of the Compound and Protein
Compound Name
4-(4-chloro-3-(4-methylpiperazine-1-carbonyl)benzylamino)quinazoline-6-carbonitrile
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Canonical SMILES
CN1CCN(C(=O)c2cc(CNc3ncnc4ccc(C#N)cc34)ccc2Cl)CC1
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Compound Formula C22H21ClN6O
Compound Structure
Protein Name
Cyclin-dependent kinase 1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CMGC protein kinase group
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CMGC protein kinase CDK family
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CMGC protein kinase CDC2 subfamily
Uniprot ID
P06493
Gene Name
CDK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
EC50 = 920 nM
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