Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-amino-N-[(1-hydroxycyclopropyl)methyl]-5-[4-(trifluoromethoxy)phenyl]sulfonylpyridine-2-carboxamide
    Show/Hide
 PubChem ID
CID: 124105806
Canonical SMILES
Nc1cc(cnc1C(=O)NCC1(O)CC1)S(=O)(=O)c1ccc(OC(F)(F)F)cc1
    Show/Hide
Compound Formula C17H16F3N3O5S
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o-
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2.8 nM
   TI
   LI
   LO
   TS