Brief Information of the Compound and Protein
Compound Name
3-amino-5-(4-fluorophenyl)sulfonyl-N-methyl-N-[(2R)-3,3,3-trifluoro-2-hydroxypropyl]pyridine-2-carboxamide
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Canonical SMILES
CN(C[C@@H](O)C(F)(F)F)C(=O)c1ncc(cc1N)S(=O)(=O)c1ccc(F)cc1
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Compound Formula C16H15F4N3O4S
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o- Homo sapiens (Human)  1
1
EC50 > 2000 nM
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