Brief Information of the Compound and Protein
Compound Name
3-amino-N-(3,3,3-trifluoro-2-hydroxypropyl)-5-[4-(trifluoromethoxy)piperidin-1-yl]sulfonylpyridine-2-carboxamide
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PubChem ID
CID: 124105798
Canonical SMILES
Nc1cc(cnc1C(=O)NCC(O)C(F)(F)F)S(=O)(=O)N1CCC(CC1)OC(F)(F)F
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Compound Formula C15H18F6N4O5S
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o- Homo sapiens (Human)  1
1
EC50 = 5 nM
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