Brief Information of the Compound and Protein
Compound Name
2-[(2-hydroxy-2-methylpropanoyl)amino]-5-(4-methoxyphenyl)sulfonylthiophene-3-carboxamide
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PubChem ID
CID: 117717847
Canonical SMILES
COc1ccc(cc1)S(=O)(=O)c1cc(C(N)=O)c(NC(=O)C(C)(C)O)s1
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Compound Formula C16H18N2O6S2
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o- Homo sapiens (Human)  1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 478 nM
   TI
   LI
   LO
   TS