Brief Information of the Compound and Protein
Compound Name
[3-amino-5-(4-fluorophenyl)sulfonylpyridin-2-yl]-[3-hydroxy-3-(trifluoromethyl)azetidin-1-yl]methanone
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PubChem ID
CID: 124106236
Canonical SMILES
Nc1cc(cnc1C(=O)N1CC(O)(C1)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1
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Compound Formula C16H13F4N3O4S
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o- Homo sapiens (Human)  1
1
EC50 = 1.1 nM
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