Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2-methyl-1-oxoisoquinolin-5-yl)-3-[[2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl]methyl]urea
    Show/Hide
Canonical SMILES
CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1cccc2c1ccn(C)c2=O)C(F)(F)F
    Show/Hide
Compound Formula C24H26F3N5O2
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 589 nM
   TI
   LI
   LO
   TS