Brief Information of the Compound and Protein
Compound Name
N-[4-(4-Methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-3-[3-((E)-2-pyrazin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-propionamide
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Canonical SMILES
CN1CCN(Cc2ccc(NC(=O)CCSc3ccc4c(/C=C/c5cnccn5)n[nH]c4c3)cc2C(F)(F)F)CC1
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Compound Formula C29H30F3N7OS
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 88 nM
   TI
   LI
   LO
   TS