Brief Information of the Compound and Protein
Compound Name
2-(3,4-Dimethoxy-phenyl)-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-acetamide
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Canonical SMILES
COc1ccc(CC(=O)Nc2nc(C)c(-c3ccc4c(/C=C/c5ccccn5)n[nH]c4c3)s2)cc1OC
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Compound Formula C28H25N5O3S
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 40 nM
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