Brief Information of the Compound and Protein
Compound Name
(E)-4-((4-Methylpiperazin-1-yl)methyl)-N-(2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)ethyl)-3-(trifluoromethyl)benzamide
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PubChem ID
CID: 155517824
Canonical SMILES
CN1CCN(Cc2ccc(C(=O)NCCSc3ccc4c(/C=C/c5ccccn5)n[nH]c4c3)cc2C(F)(F)F)CC1
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Compound Formula C30H31F3N6OS
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 370 nM
   TI
   LI
   LO
   TS