Brief Information of the Compound and Protein
Compound Name
N-{5-[3-(5-Fluoro-pyridin-3-yl)-1H-indazol-6-yl]-4-methyl-thiazol-2-yl}-2-(4-methyl-piperazin-1-yl)-acetamide
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Canonical SMILES
Cc1nc(NC(=O)CN2CCN(C)CC2)sc1-c1ccc2c(-c3cncc(F)c3)n[nH]c2c1
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Compound Formula C23H24FN7OS
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 54 nM
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