Brief Information of the Compound and Protein
Compound Name
Selitrectinib
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Canonical SMILES
C[C@@H]1CCc2ncc(F)cc2[C@H]2CCN(C2)c2ccn3ncc(c3n2)C(=O)N1
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Compound Formula C20H21FN6O
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
GI50 = 5 nM
   TI
   LI
   LO
   TS
2
GI50 = 6 nM
   TI
   LI
   LO
   TS
3
GI50 = 10 nM
   TI
   LI
   LO
   TS