Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
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 PubChem ID
CID: 129211
SID: 14855214
Canonical SMILES
CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(c1)S(N)(=O)=O
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Compound Formula C20H28N2O5S
Compound Structure
Protein Name
 Protein Info 
Alpha-1A adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P35348
Gene Name
ADRA1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.05012 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 0.32 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.029 nM
2 Ki = 0.13 nM
3 Ki = 0.19 nM