Brief Information of the Compound and Protein
Compound Name
1-[4-(4-chloro-3-fluorophenoxy)but-2-ynyl]-4-[2-(4-methoxyphenyl)phenyl]piperazine
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Canonical SMILES
COc1ccc(cc1)-c1ccccc1N1CCN(CC#CCOc2ccc(Cl)c(F)c2)CC1
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Compound Formula C27H26ClFN2O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 7
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P34969
Gene Name
HTR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 410 nM
   TI
   LI
   LO
   TS