Brief Information of the Compound and Protein
Compound Name
2-chloro-1-[2,4-diamino-6-[2-(4-ethylphenyl)ethyl]-7,8-dihydro-6H-pyrido[3,2-d]pyrimidin-5-yl]ethanone
    Show/Hide
Canonical SMILES
CCc1ccc(CCC2CCc3nc(N)nc(N)c3N2C(=O)CCl)cc1
    Show/Hide
Compound Formula C19H24ClN5O
Compound Structure
Protein Name
Methionine synthase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q99707
Gene Name
MTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  3
1
IC50 = 4460 nM
   TI
   LI
   LO
   TS
2
IC50 = 7640 nM
   TI
   LI
   LO
   TS
3
IC50 = 12100 nM
   TI
   LI
   LO
   TS