Brief Information of the Compound and Protein
Compound Name
(3R)-N-[3,5-bis(trifluoromethyl)phenyl]-5-oxo-1,4-thiazepane-3-carboxamide
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Canonical SMILES
FC(F)(F)c1cc(NC(=O)[C@@H]2CSCCC(=O)N2)cc(c1)C(F)(F)F
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Compound Formula C14H12F6N2O2S
Compound Structure
Protein Name
Metabotropic glutamate receptor 4
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31423
Gene Name
GRM4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 950 nM
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