Brief Information of the Compound and Protein
Compound Name
4-[2-(4-chlorophenyl)-5-(3,3-difluoropyrrolidine-1-carbonyl)pyrazol-3-yl]benzenesulfonamide
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Canonical SMILES
NS(=O)(=O)c1ccc(cc1)-c1cc(nn1-c1ccc(Cl)cc1)C(=O)N1CCC(F)(F)C1
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Compound Formula C20H17ClF2N4O3S
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 2200 nM
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