Brief Information of the Compound and Protein
Compound Name
N-[5-[1-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]triazol-4-yl]-2-propanoylphenyl]-5,6,7,8-tetrahydroquinoline-2-carboxamide
    Show/Hide
Canonical SMILES
CCC(=O)c1ccc(cc1NC(=O)c1ccc2CCCCc2n1)-c1cn(nn1)-c1ccc(CCN2CCc3cc(OC)c(OC)cc3C2)cc1
    Show/Hide
Compound Formula C40H42N6O4
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000781 MCF7/Topo Homo sapiens (Human)  1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS