Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10618902, Compound I-281
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 PubChem ID
CID: 90437033
Canonical SMILES
COc1cc(OC)c(F)c(c1F)-c1cc2cnc(N[C@@H]3COC[C@@H]3NC(=O)C=C)nc2n(C)c1=O
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Compound Formula C23H23F2N5O5
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 11.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.5 nM