Brief Information of the Compound and Protein
Compound Name
Apamin
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Canonical SMILES
CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H]2CCCN2C(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc3c[nH]cn3)C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N2)NC1=O
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Compound Formula C79H131N31O24S4
Compound Structure
Protein Name
Small conductance calcium-activated potassium channel protein 3
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Calcium-activated potassium channel
Uniprot ID
Q9UGI6
Gene Name
KCNN3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  2
1
EC50 = 0.36 nM
   TI
   LI
   LO
   TS
2
EC50 = 1.1 nM
   TI
   LI
   LO
   TS