Brief Information of the Compound and Protein
Compound Name
(1S,2S)-2-[[4-methoxy-6-[[2-(1H-pyrazol-3-ylamino)pyrimidin-4-yl]methoxy]-1,3-benzothiazol-2-yl]amino]cyclohexanol
    Show/Hide
Canonical SMILES
COc1cc(OCc2ccnc(Nc3cc[nH]n3)n2)cc2sc(N[C@H]3CCCC[C@@H]3O)nc12
    Show/Hide
Compound Formula C22H25N7O3S
Compound Structure
Protein Name
Macrophage colony-stimulating factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09581
Gene Name
CSF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000124 NFS-60 Mus musculus (Mouse)  1
1
IC50 = 1304 nM
   TI
   LI
   LO
   TS