Brief Information of the Compound and Protein
Compound Name
N-(4-fluoro-3-nitrophenyl)-6-methyl-2-phenylpyrimidin-4-amine
    Show/Hide
Canonical SMILES
Cc1cc(Nc2ccc(F)c(c2)[N+]([O-])=O)nc(n1)-c1ccccc1
    Show/Hide
Compound Formula C17H13FN4O2
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
IC50 = 771 nM
   TI
   LI
   LO
   TS
2
IC50 = 1010 nM
   TI
   LI
   LO
   TS