Brief Information of the Compound and Protein
Compound Name
1-[7-chloro-4-[4-(2-methylphenyl)piperazine-1-carbonyl]-3,4-dihydro-1H-isoquinolin-2-yl]-2-methylpropan-1-one
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Canonical SMILES
CC(C)C(=O)N1CC(C(=O)N2CCN(CC2)c2ccccc2C)c2ccc(Cl)cc2C1
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Compound Formula C25H30ClN3O2
Compound Structure
Protein Name
Vasopressin V1a receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Vasopressin and oxytocin receptor
Uniprot ID
P37288
Gene Name
AVPR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  2
1
IC50 = 135 nM
   TI
   LI
   LO
   TS
2
Ki = 5 nM
   TI
   LI
   LO
   TS