Brief Information of the Compound and Protein
Compound Name
(6-chloro-4-methyl-2,3-dihydroquinoxalin-1-yl)-[4-(2-methylphenyl)piperazin-1-yl]methanone
    Show/Hide
Canonical SMILES
CN1CCN(C(=O)N2CCN(CC2)c2ccccc2C)c2ccc(Cl)cc12
    Show/Hide
Compound Formula C21H25ClN4O
Compound Structure
Protein Name
Vasopressin V1a receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Vasopressin and oxytocin receptor
Uniprot ID
P37288
Gene Name
AVPR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  2
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
2
Ki = 7 nM
   TI
   LI
   LO
   TS