Brief Information of the Compound and Protein
Compound Name
N-(3-chlorophenyl)-6-[[5-methyl-4-(1-propan-2-ylpyrazol-4-yl)pyrimidin-2-yl]amino]-3,4-dihydro-1H-isoquinoline-2-carboxamide
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Canonical SMILES
CC(C)n1cc(cn1)-c1nc(Nc2ccc3CN(CCc3c2)C(=O)Nc2cccc(Cl)c2)ncc1C
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Compound Formula C27H28ClN7O
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000071 MOLM-13 Homo sapiens (Human)  1
1
IC50 = 2070 nM
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