Brief Information of the Compound and Protein
Compound Name
(E)-N,N-diethyl-4-[6-[[5-methyl-4-(1-propan-2-ylpyrazol-4-yl)pyrimidin-2-yl]amino]-3,4-dihydro-1H-isoquinolin-2-yl]but-2-enamide
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Canonical SMILES
CCN(CC)C(=O)\C=C\CN1CCc2cc(Nc3ncc(C)c(n3)-c3cnn(c3)C(C)C)ccc2C1
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Compound Formula C28H37N7O
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000071 MOLM-13 Homo sapiens (Human)  1
1
IC50 = 656 nM
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