Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9266883, 3
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 PubChem ID
CID: 118036931
Canonical SMILES
O=Cc1ccc2CCCN(C(=O)Nc3ccc(cn3)C#N)c2n1
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Compound Formula C16H13N5O2
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 108 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
2
Kd = 5 nM
   TI
   LI
   LO
   TS
3
Kd = 21 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM