Brief Information of the Compound and Protein
Compound Name
US9266883, 29
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PubChem ID
CID: 118036904
Canonical SMILES
O=Cc1nc2N(CCCc2cc1C1CC1)C(=O)Nc1ccc(cn1)C#N
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Compound Formula C19H17N5O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
Q03142
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 126 nM
   TI
   LI
   LO
   TS
2
IC50 = 317 nM
   TI
   LI
   LO
   TS