Brief Information of the Compound and Protein
Compound Name
2-[4-(3-chloro-4-fluorophenoxy)butyl]-3,4-dihydropyrazino[1,2-a]benzimidazol-1-one
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Canonical SMILES
Fc1ccc(OCCCCN2CCn3c(nc4ccccc34)C2=O)cc1Cl
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Compound Formula C20H19ClFN3O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
EC50 = 40 nM
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