Brief Information of the Compound and Protein
Compound Name
[3-(dimethylamino)-4-[(4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino]phenyl]-(4-methylpiperazin-1-yl)methanone
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PubChem ID
CID: 118286425
Canonical SMILES
CCOc1nc(Nc2ccc(cc2N(C)C)C(=O)N2CCN(C)CC2)nc2[nH]ccc12
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Compound Formula C22H29N7O2
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
TKL protein kinase group
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TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
IC50 = 3162.28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 199.53 nM