Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-[(1S,6R,8R,9R,10S,15R,17R,18R)-17-(6-aminopurin-9-yl)-3,9,12,18-tetrahydroxy-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]-1H-purin-6-one
    Show/Hide
 PubChem ID
CID: 136247207
Canonical SMILES
Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@@H](COP(O)(=O)O[C@H]2[C@H]1O)O[C@H]([C@@H]3O)n1cnc2c(O)ncnc12
    Show/Hide
Compound Formula C20H23N9O13P2
Compound Structure
Protein Name
 Protein Info 
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q86WV6
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 37000 nM
   TI
   LI
   LO
   TS
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 5100 nM
   TI
   LI
   LO
   TS
2
EC50 = 15900 nM
   TI
   LI
   LO
   TS
CL000494 THP1-Dual
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 60000 nM
   TI
   LI
   LO
   TS
CL000585 THP1-Dual KO-STING
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 62 nM
2 EC50 = 6800 nM
3 IC50 = 7.2 nM
4 IC50 = 200 nM