Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[5-chloro-2-[[2-[(dimethylamino)methyl]-3H-benzimidazol-5-yl]amino]pyrimidin-4-yl]amino]-N,N-dimethylbenzamide
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 PubChem ID
CID: 154640757
Canonical SMILES
CN(C)Cc1nc2ccc(Nc3ncc(Cl)c(Nc4ccccc4C(=O)N(C)C)n3)cc2[nH]1
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Compound Formula C23H25ClN8O
Compound Structure
Protein Name
 Protein Info 
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 3.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.8 nM
   TI
   LI
   LO
   TS
3
IC50 = 6.9 nM
   TI
   LI
   LO
   TS