Brief Information of the Compound and Protein
Compound Name
N-[(1-methylimidazol-4-yl)methyl]-4-(4-methylpiperidin-1-yl)pyrimidin-2-amine
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Canonical SMILES
CC1CCN(CC1)c1ccnc(NCc2cn(C)cn2)n1
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Compound Formula C15H22N6
Compound Structure
Protein Name
Protein O-GlcNAcase
Protein Classification
Enzyme
Uniprot ID
O60502
Gene Name
OGA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 46 nM
   TI
   LI
   LO
   TS
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
EC50 = 450 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 ~ 450 nM
2 IC50 ~ 46 nM