Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(1,3-benzodioxol-5-yl)-N-[4-phenyl-5-(4-phenylbenzoyl)-1,3-thiazol-2-yl]cyclopropane-1-carboxamide
    Show/Hide
Canonical SMILES
O=C(Nc1nc(c(s1)C(=O)c1ccc(cc1)-c1ccccc1)-c1ccccc1)C1(CC1)c1ccc2OCOc2c1
    Show/Hide
Compound Formula C33H24N2O4S
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o-
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 70 nM
   TI
   LI
   LO
   TS
2
Kd = 89300 nM
   TI
   LI
   LO
   TS