Brief Information of the Compound and Protein
Compound Name
1-(1,3-benzodioxol-5-yl)-N-[4-phenyl-5-(4-propoxybenzoyl)-1,3-thiazol-2-yl]cyclopropane-1-carboxamide
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Canonical SMILES
CCCOc1ccc(cc1)C(=O)c1sc(NC(=O)C2(CC2)c2ccc3OCOc3c2)nc1-c1ccccc1
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Compound Formula C30H26N2O5S
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o- Homo sapiens (Human)  2
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
2
Kd = 38200 nM
   TI
   LI
   LO
   TS