Brief Information of the Compound and Protein
Compound Name
2-[(5-ethyl-4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-[5-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide
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Canonical SMILES
CCc1c(C)nc(SCC(=O)Nc2ncc(s2)-c2ccc(OC)cc2)nc1O
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Compound Formula C19H20N4O3S2
Compound Structure
Protein Name
Anoctamin-1
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Calcium-activated chloride channel
Uniprot ID
Q5XXA6
Gene Name
ANO1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS