Brief Information of the Compound and Protein
Compound Name
5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid
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PubChem ID
CID: 24748573
SID: 49650657
Canonical SMILES
OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21
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Compound Formula C19H12ClN3O2
Compound Structure
Protein Name
Casein kinase II subunit alpha
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase CK2 family
Uniprot ID
P68400
Gene Name
CSNK2A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  2
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
2
IC50 = 96 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 < 3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.5 nM
2 IC50 = 1 nM
3 IC50 = 14 nM
4 IC50 = 14.7 nM
5 IC50 = 19 nM
6 IC50 = 20 nM
7 IC50 = 100 nM
8 IC50 = 2000 nM
9 Ki = 0.38 nM