Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide
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 PubChem ID
CID: 54575456
SID: 129979974
Canonical SMILES
COc1ccc(cn1)-c1nc(N2CCOCC2)c2sc(CN(C)c3ncc(cn3)C(=O)NO)cc2n1
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Compound Formula C23H24N8O4S
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 6
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class IIb
Uniprot ID
Q9UBN7
Gene Name
HDAC6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 221.75 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
2
IC50 = 34 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM
2 IC50 = 27 nM
3 IC50 = 674 nM