Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-fluoro-2-[5-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]triazolo[4,5-d]pyrimidin-3-yl]benzonitrile
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 PubChem ID
CID: 89720345
Canonical SMILES
CN1CCC(CC1)n1cc(Nc2ncc3nnn(-c4ccc(F)cc4C#N)c3n2)cn1
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Compound Formula C20H19FN10
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase 6
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase ERK3
Uniprot ID
Q16659
Gene Name
MAPK6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 55 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
2
IC50 = 244 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 177 nM