Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,3R)-3-N-[3-(4-methoxyphenyl)triazolo[4,5-d]pyrimidin-5-yl]cyclopentane-1,3-diamine
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 PubChem ID
CID: 90389598
Canonical SMILES
COc1ccc(cc1)-n1nnc2cnc(N[C@@H]3CC[C@@H](N)C3)nc12
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Compound Formula C16H19N7O
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase 6
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase ERK3
Uniprot ID
Q16659
Gene Name
MAPK6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 736 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 158 nM
   TI
   LI
   LO
   TS
2
IC50 = 274 nM
   TI
   LI
   LO
   TS
3
Kd = 180 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 157 nM