Brief Information of the Compound and Protein
Compound Name
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-fluoro-4-(6-methoxy-7-propoxyquinolin-4-yl)oxyphenyl]urea
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Canonical SMILES
CCCOc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(on4)C(C)(C)C)cc3F)c2cc1OC
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Compound Formula C27H29FN4O5
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
IC50 = 14.9 nM
   TI
   LI
   LO
   TS
2
IC50 = 19.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 54.3 nM
   TI
   LI
   LO
   TS