Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-[(22S)-17-fluoro-5-(2-hydroxypropan-2-yl)-4,22,28-trimethyl-21,27-dioxa-1,7,34-triazahexacyclo[26.2.2.16,9.110,14.02,7.015,20]tetratriaconta-2,4,6(34),8,10,12,14(33),15(20),16,18-decaen-3-yl]-2-[(2-methylpropan-2-yl)oxy]acetic acid
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 PubChem ID
CID: 118316386
Canonical SMILES
C[C@H]1CCCCOC2(C)CCN(CC2)c2c([C@H](OC(C)(C)C)C(O)=O)c(C)c(c3nc(cn23)-c2cccc(c2)-c2cc(F)ccc2O1)C(C)(C)O
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Compound Formula C41H52FN3O6
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor subfamily 1 group I member 2
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group I
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Nuclear hormone receptor subfamily 1 group I member 2
Uniprot ID
O75469
Gene Name
NR1I2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1010 nM
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